Total Synthesis of the Strychnos Alkaloid (+)-Minfiensine: Tandem Enantioselective Intramolecular Heck–Iminium Ion Cyclization

A 1,2,3,4-tetrahydro-9a,4a-(iminoethano)-9H-carbazole (4) is a central structural feature of the Strychnos alkaloid minfiensine (1) and akuammiline alkaloids such as vincorine (5) and echitamine (6). A cascade catalytic asymmetric Heck-iminium cyclization was developed that rapidly provides 3,4-dihy...

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Bibliografiska uppgifter
Huvudupphovsmän: Dounay, Amy B., Humphreys, Philip G., Overman, Larry E., Wrobleski, Aaron D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995331/
https://ncbi.nlm.nih.gov/pubmed/18303837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja800163v
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