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Prevention of tumorigenesis in p53 null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib and celecoxib

The chemopreventive effects of three agents, rexinoid bexarotene, tyrosine kinase inhibitor gefitinib and celecoxib, were tested on mammary tumor development arising in p53 null mammary epithelium. The rexinoid bexarotene was the most efficacious inhibitor as it reduced mammary tumor development by...

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Hlavní autoři: Medina, D., Kittrell, F., Hill, J., Zhang, Y., Hilsenbeck, S., Bissonette, R., Brown, P.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995265/
https://ncbi.nlm.nih.gov/pubmed/19174577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0107
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