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TRAF1 Deficiency Attenuates Atherosclerosis in Mice by Impairing Monocyte Recruitment to the Vessel Wall

BACKGROUND: Members of the tumor necrosis factor (TNF) superfamily, such as TNFα, potently promote atherogenesis in mice and humans. TNF receptor-associated factors (TRAFs) are cytoplasmic adaptor proteins for this group of cytokines. METHODS AND RESULTS: This study tested the hypothesis that TRAF1...

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Hlavní autoři: Missiou, Anna, Köstlin, Natascha, Varo, Nerea, Rudolf, Philipp, Aichele, Peter, Ernst, Sandra, Münkel, Christian, Walter, Carina, Stachon, Peter, Sommer, Benjamin, Pfeifer, Dietmar, Zirlik, Katja, MacFarlane, Lindsey, Wolf, Dennis, Tsitsikov, Erdyni, Bode, Christoph, Libby, Peter, Zirlik, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995263/
https://ncbi.nlm.nih.gov/pubmed/20421522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.895037
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