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Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitro.

Simian virus 40 (SV40) large tumor antigen (T antigen) unwinds DNA containing the SV40 origin of replication. The origin requirement for unwinding can be satisfied by the 64-base-pair SV40 core origin that supports T-antigen-dependent DNA replication both in vivo and in vitro. The core origin contai...

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Bibliografiske detaljer
Main Authors: Dean, F B, Borowiec, J A, Ishimi, Y, Deb, S, Tegtmeyer, P, Hurwitz, J
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299523/
https://ncbi.nlm.nih.gov/pubmed/2825183
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