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Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitro.

Simian virus 40 (SV40) large tumor antigen (T antigen) unwinds DNA containing the SV40 origin of replication. The origin requirement for unwinding can be satisfied by the 64-base-pair SV40 core origin that supports T-antigen-dependent DNA replication both in vivo and in vitro. The core origin contai...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dean, F B, Borowiec, J A, Ishimi, Y, Deb, S, Tegtmeyer, P, Hurwitz, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299523/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2825183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8267
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