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Defects in nuclear pore assembly lead to activation of an Aurora B–mediated abscission checkpoint

Correct assembly of nuclear pore complexes (NPCs), which directly and indirectly control nuclear environment and architecture, is vital to genomic regulation. We previously found that nucleoporin 153 (Nup153) is required for timely progression through late mitosis. In this study, we report that disr...

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Detalhes bibliográficos
Main Authors: Mackay, Douglas R., Makise, Masaki, Ullman, Katharine S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995170/
https://ncbi.nlm.nih.gov/pubmed/21098116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007124
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