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Position and motions of the S4 helix during opening of the Shaker potassium channel

The four voltage sensors in voltage-gated potassium (Kv) channels activate upon membrane depolarization and open the pore. The location and motion of the voltage-sensing S4 helix during the early activation steps and the final opening transition are unresolved. We studied Zn(2+) bridges between two...

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Autores principales: Phillips, L. Revell, Swartz, Kenton J.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995149/
https://ncbi.nlm.nih.gov/pubmed/21115696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010517
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