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Strategies to inhibit viral protein nuclear import: HIV-1 as a target

Nuclear import is a critical step in the life cycle of HIV-1. During the early (pre-integration) stages of infection, HIV-1 has to transport its pre-integration complex into the nucleus for integration into the host cell chromatin, while at the later (post-integration) stages viral regulatory protei...

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Detalhes bibliográficos
Main Authors: Levin, Aviad, Loyter, Abraham, Bukrinsky, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994963/
https://ncbi.nlm.nih.gov/pubmed/20719241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.07.010
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