Genomic RNAs of influenza viruses are held in a circular conformation in virions and in infected cells by a terminal panhandle.

The viral RNA segments in influenza virions were shown to be circular in conformation by using psoralen crosslinking methods. Electron microscopy of purified RNA following treatment of virus with the psoralen reagent 4'-aminomethyltrioxsalen (AMT) revealed circles with lengths corresponding to the i...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hsu, M T, Parvin, J D, Gupta, S, Krystal, M, Palese, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2446318/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.22.8140
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