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Removal of Heterologous Sequences from Plasmodium falciparum Mutants Using FLPe-Recombinase

Genetically-modified mutants are now indispensable Plasmodium gene-function reagents, which are also being pursued as genetically attenuated parasite vaccines. Currently, the generation of transgenic malaria-parasites requires the use of drug-resistance markers. Here we present the development of an...

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Main Authors: van Schaijk, Ben C. L., Vos, Martijn W., Janse, Chris J., Sauerwein, Robert W., Khan, Shahid M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994908/
https://ncbi.nlm.nih.gov/pubmed/21152048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015121
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