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Anti-idiotype immunization of cancer patients: modulation of the immune response.

Thirty patients with advanced colorectal carcinoma (CRC) were treated with alum-precipitated polyclonal goat anti-idiotypic antibodies (Ab2) to monoclonal anti-CRC antibody CO17-1A (Ab1) in doses between 0.5 and 4 mg per injection. All patients developed anti-anti-idiotypic antibodies (Ab3) with bin...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Herlyn, D, Wettendorff, M, Schmoll, E, Iliopoulos, D, Schedel, I, Dreikhausen, U, Raab, R, Ross, A H, Jaksche, H, Scriba, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3500471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.22.8055
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