Idiotypic cascades in cancer patients treated with monoclonal antibody CO17-1A.
We have previously shown that gastrointestinal cancer patients treated with monoclonal antibody CO17-1A (Ab1) developed anti-idiotypic antibodies (Ab2) to the Ab1. We now demonstrate that patients produce anti-anti-idiotypic antibodies (Ab3) to their autologous Ab2. Ab3 were demonstrated in culture...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2786203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3787 |
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