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Idiotypic cascades in cancer patients treated with monoclonal antibody CO17-1A.

We have previously shown that gastrointestinal cancer patients treated with monoclonal antibody CO17-1A (Ab1) developed anti-idiotypic antibodies (Ab2) to the Ab1. We now demonstrate that patients produce anti-anti-idiotypic antibodies (Ab3) to their autologous Ab2. Ab3 were demonstrated in culture...

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Detalhes bibliográficos
Main Authors: Wettendorff, M, Iliopoulos, D, Tempero, M, Kay, D, DeFreitas, E, Koprowski, H, Herlyn, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC287225/
https://ncbi.nlm.nih.gov/pubmed/2786203
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