Statins Inhibit Angiotensin II/Smad Pathway and Related Vascular Fibrosis, by a TGF-β-Independent Process

We have recently described that in an experimental model of atherosclerosis and in vascular smooth muscle cells (VSMCs) statins increased the activation of the Smad pathway by transforming growth factor-β (TGF-β), leading to an increase in TGF-β-dependent matrix accumulation and plaque stabilization...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rodrigues Díez, Raúl, Rodrigues-Díez, Raquel, Lavoz, Carolina, Rayego-Mateos, Sandra, Civantos, Esther, Rodríguez-Vita, Juan, Mezzano, Sergio, Ortiz, Alberto, Egido, Jesús, Ruiz-Ortega, Marta
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994748/
https://ncbi.nlm.nih.gov/pubmed/21152444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014145
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