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Lesion Complexity Determines Arterial Drug Distribution After Local Drug Delivery

Though stents are deployed in diseased arteries drug distribution has only been quantified in intact, non-diseased vessels. We correlated steady-state arterial drug distribution with tissue ultrastructure and composition, in abdominal aortae from atherosclerotic human autopsy specimens and rabbits w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tzafriri, Abraham R., Vukmirovic, Neda, Kolachalama, Vijaya B., Astafieva, Irina, Edelman, Elazer R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994187/
https://ncbi.nlm.nih.gov/pubmed/19925836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.11.007
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