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Impact of flow pulsatility on arterial drug distribution in stent-based therapy

Drug-eluting stents reside in a dynamic fluid environment where the extent to which drugs are distributed within the arterial wall is critically modulated by the blood flowing through the arterial lumen. Yet several factors associated with the pulsatile nature of blood flow and their impact on arter...

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Detalhes bibliográficos
Main Authors: O’Brien, Caroline C., Kolachalama, Vijaya B., Barber, Tracie J., Simmons, Anne, Edelman, Elazer R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697861/
https://ncbi.nlm.nih.gov/pubmed/23541929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.03.014
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