Bacteriophage T4 regA protein binds to mRNAs and prevents translation initiation.

The bacteriophage T4 regA protein is a translational repressor of a subset of phage mRNAs. We show here that purified regA protein binds specifically to target mRNAs near the initiating AUG and occludes binding of ribosomes. Translational repression by regA protein diminishes expression of many gene...

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Bibliografiska uppgifter
Huvudupphovsmän: Winter, R B, Morrissey, L, Gauss, P, Gold, L, Hsu, T, Karam, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC299406/
https://ncbi.nlm.nih.gov/pubmed/3120177
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