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Co-Stimulation Blockade Inhibits Allergic Sensitization but does not Affect Established Allergy in a Murine Model of Grass Pollen Allergy
Type I allergy is characterized by the development of an initial Th2-dependent allergen-specific IgE response, which is boosted upon subsequent allergen encounter. While the immediate symptoms of allergy are mainly IgE-mediated, allergen-specific T cell responses contribute to the late-phase as well...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993922/ https://ncbi.nlm.nih.gov/pubmed/17339493 |
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