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Co-Stimulation Blockade Inhibits Allergic Sensitization but does not Affect Established Allergy in a Murine Model of Grass Pollen Allergy

Type I allergy is characterized by the development of an initial Th2-dependent allergen-specific IgE response, which is boosted upon subsequent allergen encounter. While the immediate symptoms of allergy are mainly IgE-mediated, allergen-specific T cell responses contribute to the late-phase as well...

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Sonraí Bibleagrafaíochta
Main Authors: Linhart, Birgit, Bigenzahn, Sinda, Hartl, Arnulf, Lupinek, Christian, Thalhamer, Josef, Valenta, Rudolf, Wekerle, Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993922/
https://ncbi.nlm.nih.gov/pubmed/17339493
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