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P53 levels govern the choice between senescence and quiescence
The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling.
Uloženo v:
| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993792/ |
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