Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures

Under certain experimental conditions, neurotrophic factors may reduce epileptogenesis. We have previously reported that local, intrahippocampal supplementation of fibroblast growth factor-2 (FGF-2) and brain-derived neurotrophic factor (BDNF) increases neurogenesis, reduces neuronal loss, and reduc...

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Detalhes bibliográficos
Principais autores: Bovolenta, Roberta, Zucchini, Silvia, Paradiso, Beatrice, Rodi, Donata, Merigo, Flavia, Mora, Graciela Navarro, Osculati, Francesco, Berto, Elena, Marconi, Peggy, Marzola, Andrea, Fabene, Paolo F, Simonato, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993685/
https://ncbi.nlm.nih.gov/pubmed/21087489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-81
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