Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas.

We have previously reported the isolation of a human breast cancer cell line resistant to doxorubicin (adriamycin; AdrR MCF-7 cells) that has also developed the phenotype of multidrug resistance (MDR). MDR in this cell line is associated with increased expression of mdr (P glycoprotein) gene sequenc...

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Detalhes bibliográficos
Main Authors: Fairchild, C R, Ivy, S P, Rushmore, T, Lee, G, Koo, P, Goldsmith, M E, Myers, C E, Farber, E, Cowan, K H
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299368/
https://ncbi.nlm.nih.gov/pubmed/2890168
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