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Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP

The centrosome is the principal microtubule organizing center (MTOC) of animal cells [1]. Accurate centrosome duplication is fundamental for genome integrity and entails the formation of one procentriole next to each existing centriole, once per cell cycle. The procentriole then elongates to eventua...

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Main Authors: Kohlmaier, Gregor, Lončarek, Jadranka, Meng, Xing, McEwen, Bruce F., Mogensen, Mette, Spektor, Alexander, Dynlacht, Brian D., Khodjakov, Alexey, Gönczy, Pierre
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993638/
https://ncbi.nlm.nih.gov/pubmed/19481460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.018
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