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T-cadherin is critical for adiponectin-mediated cardioprotection in mice

The circulating, adipocyte-secreted hormone adiponectin (APN) exerts protective effects on the heart under stress conditions. The receptors binding APN to cardiac tissue, however, have remained elusive. Here, we report that the glycosyl phosphatidylinositol–anchored cell surface glycoprotein T-cadhe...

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Detalhes bibliográficos
Main Authors: Denzel, Martin S., Scimia, Maria-Cecilia, Zumstein, Philine M., Walsh, Kenneth, Ruiz-Lozano, Pilar, Ranscht, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993592/
https://ncbi.nlm.nih.gov/pubmed/21041950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43464
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