Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice

Mutations in the dysferlin gene underlie a group of autosomal recessive muscle-wasting disorders denoted as dysferlinopathies. Dysferlin has been shown to play roles in muscle membrane repair and muscle regeneration, both of which require vesicle-membrane fusion. However, the mechanism by which musc...

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Autori principali: Han, Renzhi, Frett, Ellie M., Levy, Jennifer R., Rader, Erik P., Lueck, John D., Bansal, Dimple, Moore, Steven A., Ng, Rainer, Beltrán-Valero de Bernabé, Daniel, Faulkner, John A., Campbell, Kevin P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993587/
https://ncbi.nlm.nih.gov/pubmed/21060153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42390
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