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Deregulation of the Pit-1 transcription factor in human breast cancer cells promotes tumor growth and metastasis
The Pit-1 transcription factor (also know as POU1F1) plays a critical role in cell differentiation during organogenesis of the anterior pituitary in mammals and is a transcriptional activator for pituitary gene transcription. Increased expression of Pit-1 has been reported in human tumorigenic breas...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993584/ https://ncbi.nlm.nih.gov/pubmed/21060149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42015 |
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