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Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus
Streptomyces clavuligerus, an industrially important producer of clavulanate as well as cephem antibiotics, also produces the N-acylated dithiolopyrrolone antibiotic holomycin, a reported inhibitor of RNA synthesis. The genome sequence of S. clavuligerus ATCC 27064 was examined for a potential biosy...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993409/ https://ncbi.nlm.nih.gov/pubmed/21041678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014140107 |
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