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A network connecting Runx2, SATB2, and the miR-23a∼27a∼24-2 cluster regulates the osteoblast differentiation program

Induced osteogenesis includes a program of microRNAs (miRs) to repress the translation of genes that act as inhibitors of bone formation. How expression of bone-related miRs is regulated remains a compelling question. Here we report that Runx2, a transcription factor essential for osteoblastogenesis...

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Bibliografske podrobnosti
Main Authors: Hassan, Mohammad Q., Gordon, Jonathan A. R., Beloti, Marcio M., Croce, Carlo M., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993380/
https://ncbi.nlm.nih.gov/pubmed/20980664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007698107
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