Assembly of a functional Machupo virus polymerase complex

Segmented negative-sense viruses of the family Arenaviridae encode a large polymerase (L) protein that contains all of the enzymatic activities required for RNA synthesis. These activities include an RNA-dependent RNA polymerase (RdRP) and an RNA endonuclease that cleaves capped primers from cellula...

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Autors principals: Kranzusch, Philip J., Schenk, Andreas D., Rahmeh, Amal A., Radoshitzky, Sheli R., Bavari, Sina, Walz, Thomas, Whelan, Sean P. J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993349/
https://ncbi.nlm.nih.gov/pubmed/20978208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007152107
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