Down-Regulation of the Oncogene Cyclin D1 Increases Migratory Capacity in Breast Cancer and Is Linked to Unfavorable Prognostic Features

The oncogene cyclin D1 is highly expressed in many breast cancers and, despite its proliferation-activating properties, it has been linked to a less malignant phenotype. To clarify this observation, we focused on two key components of malignant behavior, migration and proliferation, and observed tha...

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Detalhes bibliográficos
Main Authors: Lehn, Sophie, Tobin, Nicholas P., Berglund, Pontus, Nilsson, Kristina, Sims, Andrew H., Jirström, Karin, Härkönen, Pirkko, Lamb, Rebecca, Landberg, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993304/
https://ncbi.nlm.nih.gov/pubmed/20971731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100303
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