Small Interfering RNAs Induce Target-Independent Inhibition of Tumor Growth and Vasculature Remodeling in a Mouse Model of Hepatocellular Carcinoma

RNA interference mediated by small interfering RNAs (siRNAs) has emerged as a potential therapeutic approach to treat various diseases, including cancer. Recent studies with several animal models of posttraumatic revascularization demonstrated that synthetic siRNAs may produce therapeutic effects in...

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Autors principals: Bergé, Mathieu, Bonnin, Philippe, Sulpice, Eric, Vilar, José, Allanic, David, Silvestre, Jean-Sébastien, Lévy, Bernard I., Tucker, Gordon C., Tobelem, Gérard, Merkulova-Rainon, Tatyana
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993283/
https://ncbi.nlm.nih.gov/pubmed/20971743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100157
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