Activation of Phosphatidylinositol 3-Kinase/Akt and Impairment of Nuclear Factor-κB : Molecular Mechanisms Behind the Arrested Maturation/Activation State of Leishmania infantum-Infected Dendritic Cells

Understanding the complex interactions between Leishmania and dendritic cells (DCs) is central to the modulation of the outcome of this infection, given that an effective immune response against Leishmania is dependent on the successful activation and maturation of DCs. We report here that Leishmani...

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Hlavní autoři: Neves, Bruno Miguel, Silvestre, Ricardo, Resende, Mariana, Ouaissi, Ali, Cunha, Joana, Tavares, Joana, Loureiro, Inês, Santarém, Nuno, Silva, Ana Marta, Lopes, Maria Celeste, Cruz, Maria Teresa, Cordeiro da Silva, Anabela
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993270/
https://ncbi.nlm.nih.gov/pubmed/21037075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100367
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