Identification of Aneuploidy-tolerating Mutations

Aneuploidy causes a proliferative disadvantage in all normal cells analyzed to date, yet this condition is associated with a disease characterized by unabated proliferative potential, cancer. The mechanisms that allow cancer cells to tolerate the adverse effects of aneuploidy are not known. To probe...

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Main Authors: Torres, Eduardo M., Dephoure, Noah, Panneerselvam, Amudha, Tucker, Cheryl M., Whittaker, Charles A., Gygi, Steven P., Dunham, Maitreya J., Amon, Angelika
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993244/
https://ncbi.nlm.nih.gov/pubmed/20850176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.08.038
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