Local angiotensin II aggravates cardiac remodeling in hypertension

Angiotensin II (ANG II) contributes to hypertension, cardiac hypertrophy, fibrosis, and dysfunction; however, it is difficult to separate the cardiac effect of ANG II from its hemodynamic action in vivo. To overcome the limitations, we used transgenic mice with cardiac-specific expression of a trans...

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Detalhes bibliográficos
Main Authors: Xu, Jiang, Carretero, Oscar A., Liao, Tang-Dong, Peng, Hongmei, Shesely, Edward G., Xu, Junxiao, Liu, Thomas S., Yang, James J., Reudelhuber, Timothy L., Yang, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993216/
https://ncbi.nlm.nih.gov/pubmed/20833959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00538.2010
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