Intestine-specific transcription factor Cdx2 induces E-cadherin function by enhancing the trafficking of E-cadherin to the cell membrane

Cdx2 is an intestine-specific transcription factor required for normal intestinal epithelium development. Cdx2 regulates the expression of intestine-specific genes and induces cell adhesion and columnar morphogenesis. Cdx2 also has tumor-suppressor properties, including the reduction of colon cancer...

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Bibliografiske detaljer
Main Authors: Funakoshi, Shinsuke, Kong, Jianping, Crissey, Mary Ann, Dang, Long, Dang, Duyen, Lynch, John P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2010
Fag:
Mucosal Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993167/
https://ncbi.nlm.nih.gov/pubmed/20671195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00297.2010
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