The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium

Cationic host defense peptides are key, evolutionarily conserved components of the innate immune system. The human cathelicidin LL-37 is an important cationic host defense peptide up-regulated in infection and inflammation, specifically in the human lung, and was shown to enhance the pulmonary clear...

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Main Authors: Barlow, Peter G., Beaumont, Paula E., Cosseau, Celine, Mackellar, Annie, Wilkinson, Thomas S., Hancock, Robert E. W., Haslett, Chris, Govan, John R. W., Simpson, A. John, Davidson, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993089/
https://ncbi.nlm.nih.gov/pubmed/20097832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0250OC
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