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The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system

The human cathelicidin LL-37 is a cationic host defense peptide (antimicrobial peptide) expressed primarily by neutrophils and epithelial cells. This peptide, up-regulated under conditions of inflammation, has immunomodulatory and antimicrobial functions. We demonstrate that LL-37 is a potent inhibi...

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Autors principals: Barlow, Peter G., Li, Yuexin, Wilkinson, Thomas S., Bowdish, Dawn M. E., Lau, Y. Elaine, Cosseau, Celine, Haslett, Christopher, Simpson, A. John, Hancock, Robert E. W., Davidson, Donald J.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851551/
https://ncbi.nlm.nih.gov/pubmed/16793910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1005560
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