The Host Defense Peptide LL-37 Selectively Permeabilizes Apoptotic Leukocytes

LL-37 is a cationic host defense peptide that is highly expressed during acute inflammation and that kills bacteria by poorly defined mechanisms, resulting in permeabilization of microbial membranes. High concentrations of LL-37 have also been reported to have cytotoxic effects against eukaryotic ce...

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Main Authors: Björstad, Åse, Askarieh, Galia, Brown, Kelly L., Christenson, Karin, Forsman, Huamei, Önnheim, Karin, Li, Hsin-Ni, Teneberg, Susann, Maier, Olaf, Hoekstra, Dick, Dahlgren, Claes, Davidson, Donald J., Bylund, Johan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650579/
https://ncbi.nlm.nih.gov/pubmed/19075071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01310-08
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