Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

The virulence and pathogenesis mechanisms of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains depend on a newly described group of phenol-soluble modulin (PSM) peptides (the PSMα peptides) with cytolytic activity. These toxins are α-helical peptides with a formyl gr...

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Bibliografiset tiedot
Päätekijät: Forsman, Huamei, Christenson, Karin, Bylund, Johan, Dahlgren, Claes
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370598/
https://ncbi.nlm.nih.gov/pubmed/22431645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05906-11
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