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Reversible, calcium-dependent membrane association of human leukocyte 5-lipoxygenase.

Maximal activity of human leukocyte 5-lipoxygenase requires Ca2+, ATP, a microsomal membrane preparation, and two cytosolic stimulatory factors. We report here some effects of Ca2+ on the physical properties of the 5-lipoxygenase. When leukocytes were homogenized in the presence of 2 mM EDTA, 5-lipo...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rouzer, C A, Samuelsson, B
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3118366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.21.7393
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