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Reversible, calcium-dependent membrane association of human leukocyte 5-lipoxygenase.

Maximal activity of human leukocyte 5-lipoxygenase requires Ca2+, ATP, a microsomal membrane preparation, and two cytosolic stimulatory factors. We report here some effects of Ca2+ on the physical properties of the 5-lipoxygenase. When leukocytes were homogenized in the presence of 2 mM EDTA, 5-lipo...

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Detalhes bibliográficos
Main Authors: Rouzer, C A, Samuelsson, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299302/
https://ncbi.nlm.nih.gov/pubmed/3118366
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