Effect of plant neutrophil elastase inhibitor on leucocyte migration, adhesion and cytokine release in inflammatory conditions

BACKGROUND AND PURPOSE: The serine and cysteine peptidase inhibitor, BbCI, isolated from Bauhinia bauhinioides seeds, is similar to the classical plant Kunitz inhibitor, STI, but lacks disulphide bridges and methionine residues. BbCI blocks activity of the serine peptidases, elastase (K(iapp) 5.3 nM...

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Hlavní autoři: Oliveira, C, Navarro-Xavier, RA, Anjos-Vallota, EA, Martins, JO, Silveira, VLF, Gonçalves, LRC, Araújo, MS, Motta, G, Sannomiya, P, Oliva, MLV
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992903/
https://ncbi.nlm.nih.gov/pubmed/20860667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00924.x
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