Over-expression of mitogen-activated protein kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells

BACKGROUND AND PURPOSE: We assessed the effects of over-expressing the dual-specific phosphatase, mitogen-activated protein (MAP) kinase phosphatase-2 (MKP-2), in human umbilical vein endothelial cells (HUVECs) on inflammatory protein expression and apoptosis, two key features of endothelial dysfunc...

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Detalles Bibliográficos
Main Authors: Al-Mutairi, Mashael, Al-Harthi, Sameer, Cadalbert, Laurence, Plevin, Robin
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992895/
https://ncbi.nlm.nih.gov/pubmed/20860659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00952.x
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