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Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25

Acyl-CoA synthases are important for lipid synthesis and breakdown, generation of signaling molecules and lipid modification of proteins, highlighting the challenge of understanding metabolic pathways within intact organisms. From a C. elegans mutagenesis screen, we found that loss of ACS-3, a long-...

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Detalhes bibliográficos
Main Authors: Mullaney, Brendan, Ashrafi, Kaveh
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992884/
https://ncbi.nlm.nih.gov/pubmed/20889131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.08.013
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