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Histone Deacetylase Inhibitors Modulates the Induction and Expression of Amphetamine-induced Behavioral Sensitization Partially Through an Associated Learning of the Environment in Mice

The behavioral sensitization produced by repeated amphetamine treatment may represent the neural adaptations underlying some of the features of psychosis and addiction in humans. Chromatin modification (specifically histone hyperacetylation) was recently recognized as an important regulator of psych...

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Bibliographic Details
Main Authors: Kalda, Anti, Heidmets, Lenne-Triin, Shen, Hai-ying, Zharkovsky, Alexander, Chen, Jiang-Fan
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992845/
https://ncbi.nlm.nih.gov/pubmed/17477979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2007.03.027
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