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Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation
Two GPCRs (G-protein-coupled receptors), TRHR (thyrotropin-releasing hormone receptor) and β(2)AR (β(2)-adrenergic receptor), are regulated in distinct manners. Following agonist binding, TRHR undergoes rapid phosphorylation attributable to GRKs (GPCR kinases); β(2)AR is phosphorylated by both secon...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992812/ https://ncbi.nlm.nih.gov/pubmed/20345371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100139 |
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