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Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance

OBJECTIVE: The liver plays a critical role in integrating and controlling glucose metabolism. Thus, it is important that the liver receive and react to signals from other tissues regarding the nutrient status of the body. Leptin, which is produced and secreted from adipose tissue, is a hormone that...

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Main Authors: Huynh, Frank K., Levi, Jasna, Denroche, Heather C., Gray, Sarah L., Voshol, Peter J., Neumann, Ursula H., Speck, Madeleine, Chua, Streamson C., Covey, Scott D., Kieffer, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992763/
https://ncbi.nlm.nih.gov/pubmed/20876720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0074
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