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A Soluble Guanylate Cyclase–Dependent Mechanism Is Involved in the Regulation of Net Hepatic Glucose Uptake by Nitric Oxide in Vivo

OBJECTIVE: We previously showed that elevating hepatic nitric oxide (NO) levels reduced net hepatic glucose uptake (NHGU) in the presence of portal glucose delivery, hyperglycemia, and hyperinsulinemia. The aim of the present study was to determine the role of a downstream signal, soluble guanylate...

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Detalhes bibliográficos
Main Authors: An, Zhibo, Winnick, Jason J., Farmer, Ben, Neal, Doss, Lautz, Margaret, Irimia, Jose M., Roach, Peter J., Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992759/
https://ncbi.nlm.nih.gov/pubmed/20823104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0138
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