Trophoblast Glycoprotein: Possible Candidate Mediating Podocyte Injuries in Glomerulonephritis

BACKGROUND: Trophoblast glycoprotein (Tpbg), a 72-kDa transmembrane glycoprotein, is known to regulate the phenotypes of epithelial cells by modifying actin organization and cell motility. Recently, a microarray study showed that Tpbg is upregulated in Thy1 glomerulonephritis (Thy1 GN). We hypothesi...

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Autori principali: Murakami, Taichi, Abe, Hideharu, Nagai, Kojiro, Tominaga, Tatsuya, Takamatsu, Norimichi, Araoka, Toshikazu, Kishi, Seiji, Takahashi, Toshikazu, Mima, Akira, Takai, Yoshimi, Kopp, Jeffrey B., Doi, Toshio
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2010
Soggetti:
Original Report: Laboratory Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992649/
https://ncbi.nlm.nih.gov/pubmed/20980737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321366
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