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Identification and Characterization of Novel Inhibitors of mPTPB, an Essential Virulent Phosphatase from Mycobacterium tuberculosis

[Image: see text] Mycobacterium protein tyrosine phosphatase B (mPTPB) is an essential virulence factor required for Mycobacterium tuberculosis (Mtb) survival in host macrophages. Consequently, mPTPB represents an exciting new target with a completely novel mechanism of action. We screened a library...

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Main Authors: Chen, Lan, Zhou, Bo, Zhang, Sheng, Wu, Li, Wang, Yuehong, Franzblau, Scott G., Zhang, Zhong-Yin
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2010
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992434/
https://ncbi.nlm.nih.gov/pubmed/21116447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1001135
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