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Biological and biochemical consequences of global deletion of exon 3 from the ERα gene

To address issues resulting from α estrogen receptor-knockout (αERKO) residual N-terminal truncated estrogen receptor α, and to allow tissue-selective deletion of ERα, we generated loxP-flanked exon 3 mice. Initial characterization of global sox2 cre-derived exon 3-deleted Ex3αERKO mice indicated no...

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Autori principali: Hewitt, Sylvia C., Kissling, Grace E., Fieselman, Karen E., Jayes, Friederike L., Gerrish, Kevin E., Korach, Kenneth S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992373/
https://ncbi.nlm.nih.gov/pubmed/20667977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-163428
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