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Challenges and Opportunities for New Protein Crystallization Strategies in Structure-Based Drug Design

Structure-based drug design (SBDD) has emerged as a valuable pharmaceutical lead discovery tool, showing potential for accelerating the discovery process, while reducing developmental costs and boosting potencies of the drug that is ultimately selected. SBDD is a iterative, rational, lead compound s...

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Hlavní autoři: Grey, Jessica, Thompson, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992350/
https://ncbi.nlm.nih.gov/pubmed/21116481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2010.515583
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